NEW YORK (AP) — When the Council of Fashion Designers of America launched its breast-cancer initiative 14 years ago, it tapped Ralph Lauren to create the shirt that would go on to raise $2 million. With that same number in its sights, Lauren again designed the garment the industry is counting on to attract attention — and buyers from around the globe.

It’s one of his classic colorful polo shirts, but instead of a Lauren pony on the chest, you’ll find the Fashion Targets Breast Cancer bulls-eye. (The pony can still be found near the shirt’s hem.)

Lauren said he first participated in the campaign at the request of the late Washington Post fashion critic Nina Hyde, who fought the disease. He’s now doing it because it’s a global initiative that he believes can grow even stronger.

‘‘I am very honored to have been part of FTBC’s history and I hope we can continue to do great work,’’ Lauren said in an e-mail to the Associated Press.

The biggest change to the campaign this year is its global scope. The Lauren shirt — with other exclusive garments by Diane von Furstenberg, Rachel Roy and Oscar de la Renta to come later in the year — is being sold by online retailer Net-a-Porter, which ships to customers in 170 countries.

One-hundred percent of net profits from the sale of the items will benefit Fashion Targets Breast Cancer. The Lauren shirt costs $75 and is available in red, white, green, yellow and aqua blue.

Net-a-Porter founder Natalie Massenet says the time was right for her 7-year-old company to help with a charitable initiative. Breast-cancer awareness seemed a natural match considering 80 percent of her employees are women. ‘‘Putting the initiative on our site can give it global exposure,’’ she says. ‘‘The disease doesn’t have geographical boundaries.’’

Proceeds donated will be kept in the country from where the shirt was bought.

‘‘So many times a little guilt comes with a fashion purchase — it’s pleasure and guilt — but this is one purchase with no guilt,’’ Massenet says. ‘‘And it will be so cute next summer with your little white shorts.’’

The Fashion Targets Breast Cancer ad was given free space in many major fashion magazines, and top photographer Patrick Demarchelier, creative director David Lipman and models Daria Werbowy, Lily Donaldson, Lily Cole, Du Juan and Sasha Pivovarova all donated their time. A behind-the-scenes video from the shoot can be seen at Style.com.

Proceeds raised from effort, including the $40 million raised over the past 14 years, have gone to various breast cancer charities in 13 countries that specialize in health care, education and outreach programs.